Stem Cells
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Reprints/Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Badiavas, E. V.
Right arrow Articles by Kaji, H.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Badiavas, E. V.
Right arrow Articles by Kaji, H.

International Journal of Cell Cloning, Vol 7, 179-189, Copyright © 1989 by AlphaMed Press

ORIGINAL ARTICLES

An in vivo analysis of c-myc and c-fos expression during terminal erythroid differentiation in mouse spleen progenitors

EV Badiavas and H Kaji
Department of Pharmacology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.

Using thiamphenicol and scheduled bleeding, we were able to induce an adequate number of erythroid stem cells (CFU-e) in mice in order to conduct an in vivo study of the changing expression of c-myc and c-fos oncogenes during erythropoiesis. Results indicated that c-myc and c-fos are active in erythropoiesis and have a similar pattern of expression. A large decrease in expression of both c-myc and c-fos occurs when erythroid cells begin the biochemical transition into mature phenotypes, i.e., when RNA synthesis is down-regulated.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
STEM CELLS THE ONCOLOGIST CME ALPHAMED PRESS JOURNALS

Copyright © 1989 by AlphaMed Press.