Stem Cells Online -- Table of Contents Volume 26, Number 5, 2008

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EDITORIAL

STEM CELLS Appoints Four Associate Editors: Donald G. Phinney, Miodrag Stojkovic
Stem Cells May 1 2008: 1095 - 1096 . [Full Text] [PDF] OPEN ACCESS ARTICLE

EMBRYONIC STEM CELLS

Hedgehog Serves as a Mitogen and Survival Factor During Embryonic Stem Cell Neurogenesis: Chunyu Cai, Jeffrey Thorne, Laura Grabel
Stem Cells May 1 2008: 1097 - 1108 . [Abstract] [Full Text] [PDF] [Supplemental Data] OPEN ACCESS ARTICLE

Alkaline Phosphatase-Positive Colony Formation Is a Sensitive, Specific, and Quantitative Indicator of Undifferentiated Human Embryonic Stem Cells: Michael D. O'Connor, Melanie D. Kardel, Ioulia Iosfina, David Youssef, Min Lu, Michael M. Li, Suzanne Vercauteren, Andras Nagy, Connie J. Eaves
Stem Cells May 1 2008: 1109 - 1116 . [Abstract] [Full Text] [PDF] [Supplemental Data] OPEN ACCESS ARTICLE

Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells: Sadhana Agarwal, Katherine L. Holton, Robert Lanza
Stem Cells May 1 2008: 1117 - 1127 . [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE

A Comparison of Protocols Used to Generate Insulin-Producing Cell Clusters from Mouse Embryonic Stem Cells: Ashleigh S. Boyd, Douglas C. Wu, Yasuyuki Higashi, Kathryn J. Wood
Stem Cells May 1 2008: 1128 - 1137 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Leukotriene Synthesis Is Required for Hedgehog-Dependent Neurite Projection in Neuralized Embryoid Bodies but Not for Motor Neuron Differentiation: Maarten F. Bijlsma, Maikel P. Peppelenbosch, C. Arnold Spek, Henk Roelink
Stem Cells May 1 2008: 1138 - 1145 . [Abstract] [Full Text] [PDF]

Lysophosphatidic Acid Inhibits Neuronal Differentiation of Neural Stem/Progenitor Cells Derived from Human Embryonic Stem Cells: Mirella Dottori, Jessie Leung, Ann M. Turnley, Alice Pébay
Stem Cells May 1 2008: 1146 - 1154 . [Abstract] [Full Text] [PDF] [Supplemental Data]

BAF250B-Associated SWI/SNF Chromatin-Remodeling Complex Is Required to Maintain Undifferentiated Mouse Embryonic Stem Cells: Zhijiang Yan, Zhong Wang, Lioudmila Sharova, Alexei A. Sharov, Chen Ling, Yulan Piao, Kazuhiro Aiba, Ryo Matoba, Weidong Wang, Minoru S. H. Ko
Stem Cells May 1 2008: 1155 - 1165 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Instability of Retroviral DNA Methylation in Embryonic Stem Cells: Shigeru Minoguchi, Hideo Iba
Stem Cells May 1 2008: 1166 - 1173 . [Abstract] [Full Text] [PDF] [Supplemental Data]

STEM CELL GENOMICS AND PROTEOMICS

Epigenetic Marking Prepares the Human HOXA Cluster for Activation During Differentiation of Pluripotent Cells: Stuart P. Atkinson, Christoph M. Koch, Gayle K. Clelland, Sarah Willcox, Joanna C. Fowler, Rebecca Stewart, Majlinda Lako, Ian Dunham, Lyle Armstrong
Stem Cells May 1 2008: 1174 - 1185 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Functional Network Reconstruction Reveals Somatic Stemness Genetic Maps and Dedifferentiation-Like Transcriptome Reprogramming Induced by GATA2: Tse-Shun Huang, Jui-Yu Hsieh, Yu-Hsuan Wu, Chih-Hung Jen, Yang-Hwei Tsuang, Shih-Hwa Chiou, Jukka Partanen, Heidi Anderson, Taina Jaatinen, Yau-Hua Yu, Hsei-Wei Wang
Stem Cells May 1 2008: 1186 - 1201 . [Abstract] [Full Text] [PDF] [Supplemental Data]

THE STEM CELL NICHE

Activation of Wnt Signaling in Hematopoietic Regeneration: Kendra L. Congdon, Carlijn Voermans, Emily C. Ferguson, Leah N. DiMascio, Mweia Uqoezwa, Chen Zhao, Tannishtha Reya
Stem Cells May 1 2008: 1202 - 1210 . [Abstract] [Full Text] [PDF] [Supplemental Data] OPEN ACCESS ARTICLE

Carboxypeptidase M Expressed by Human Bone Marrow Cells Cleaves the C-Terminal Lysine of Stromal Cell-Derived Factor-1 ${alpha}$ : Another Player in Hematopoietic Stem/Progenitor Cell Mobilization?: Leah Marquez-Curtis, Ali Jalili, Kathleen Deiteren, Neeta Shirvaikar, Anne-Marie Lambeir, Anna Janowska-Wieczorek
Stem Cells May 1 2008: 1211 - 1220 . [Abstract] [Full Text] [PDF]

Induction of Neurogenesis in Nonconventional Neurogenic Regions of the Adult Central Nervous System by Niche Astrocyte-Produced Signals: Jianwei Jiao, Dong Feng Chen
Stem Cells May 1 2008: 1221 - 1230 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Mobilization of Hematopoietic Progenitor Cells by Yeast-Derived β-Glucan Requires Activation of Matrix Metalloproteinase-9: Daniel E. Cramer, Stephanie Wagner, Bing Li, Jingjing Liu, Richard Hansen, Ryan Reca, Wan Wu, Ewa Zuba Surma, Damian A. Laber, Mariusz Z. Ratajczak, Jun Yan
Stem Cells May 1 2008: 1231 - 1240 . [Abstract] [Full Text] [PDF]

TISSUE-SPECIFIC STEM CELLS

Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Gland: Contrasting Roles of c-Myc and β-Catenin: Cristina Lo Celso, Melanie A. Berta, Kristin M. Braun, Michaela Frye, Stephen Lyle, Christos C. Zouboulis, Fiona M. Watt
Stem Cells May 1 2008: 1241 - 1252 . [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE

Reciprocal Intraepithelial Interactions Between TP63 and Hedgehog Signaling Regulate Quiescence and Activation of Progenitor Elaboration by Mammary Stem Cells: Na Li, Samer Singh, Pratima Cherukuri, Hua Li, Ziqiang Yuan, Leif W. Ellisen, Baolin Wang, David Robbins, James DiRenzo
Stem Cells May 1 2008: 1253 - 1264 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Hes1 Regulates Corneal Development and the Function of Corneal Epithelial Stem/Progenitor Cells: Takahiro Nakamura, Toshiyuki Ohtsuka, Eiichi Sekiyama, Leanne J. Cooper, Hiroshi Kokubu, Nigel J. Fullwood, Yann Barrandon, Ryoichiro Kageyama, Shigeru Kinoshita
Stem Cells May 1 2008: 1265 - 1274 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Immunogenicity of Human Mesenchymal Stem Cells in HLA-Class I-Restricted T-Cell Responses Against Viral or Tumor-Associated Antigens: Fabio Morandi, Lizzia Raffaghello, Giovanna Bianchi, Francesca Meloni, Annalisa Salis, Enrico Millo, Soldano Ferrone, Vincenzo Barnaba, Vito Pistoia
Stem Cells May 1 2008: 1275 - 1287 . [Abstract] [Full Text] [PDF]

Glycogen Synthase Kinase-3β Inhibition Preserves Hematopoietic Stem Cell Activity and Inhibits Leukemic Cell Growth: Tiffany Holmes, Tracey A. O'Brien, Robert Knight, Robert Lindeman, Sylvie Shen, Emma Song, Geoff Symonds, Alla Dolnikov
Stem Cells May 1 2008: 1288 - 1297 . [Abstract] [Full Text] [PDF]

Horizontal Basal Cells Are Multipotent Progenitors in Normal and Injured Adult Olfactory Epithelium: Naomi Iwai, Zhijian Zhou, Dennis R. Roop, Richard R. Behringer
Stem Cells May 1 2008: 1298 - 1306 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Bone Marrow Multipotent Mesenchymal Stromal Cells Do Not Reduce Fibrosis or Improve Function in a Rat Model of Severe Chronic Liver Injury: Adriana B. Carvalho, Luiz Fernando Quintanilha, Juliana V. Dias, Bruno D. Paredes, Elida G. Mannheimer, Felipe G. Carvalho, Karina D. Asensi, Bianca Gutfilen, Lea Mirian B. Fonseca, Celia Maria C. Resende, Guilherme F. M. Rezende, Christina M. Takiya, Antonio Carlos Campos de Carvalho, Regina C. S. Goldenberg
Stem Cells May 1 2008: 1307 - 1314 . [Abstract] [Full Text] [PDF]

Evolution of the c-kit-Positive Cell Response to Pathological Challenge in the Myocardium: Jenna Fransioli, Brandi Bailey, Natalie A. Gude, Christopher T. Cottage, John A. Muraski, Gregory Emmanuel, Weitao Wu, Roberto Alvarez, Marta Rubio, Sergio Ottolenghi, Erik Schaefer, Mark A. Sussman
Stem Cells May 1 2008: 1315 - 1324 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolic Flexibility Permits Mesenchymal Stem Cell Survival in an Ischemic Environment: Louise A. Mylotte, Angela M. Duffy, Mary Murphy, Timothy O'Brien, Afshin Samali, Frank Barry, Eva Szegezdi
Stem Cells May 1 2008: 1325 - 1336 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Conditional Stabilization of β-Catenin Expands the Pool of Lung Stem Cells: Susan D. Reynolds, Anna C. Zemke, Adam Giangreco, Brian L. Brockway, Roxana M. Teisanu, Jeffrey A. Drake, Thomas Mariani, Peter Y.P. Di, Mark M. Taketo, Barry R. Stripp
Stem Cells May 1 2008: 1337 - 1346 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Embryonic Porcine Liver as a Source for Transplantation: Advantage of Intact Liver Implants over Isolated Hepatoblasts in Overcoming Homeostatic Inhibition by the Quiescent Host Liver: Helena Katchman, Orna Tal, Smadar Eventov-Friedman, Elias Shezen, Anna Aronovich, Dalit Tchorsh, Sivan Cohen, Alexander Shtabsky, Gil Hecht, Benjamin Dekel, Enrique Freud, Yair Reisner
Stem Cells May 1 2008: 1347 - 1355 . [Abstract] [Full Text] [PDF]

TRANSLATIONAL AND CLINICAL RESEARCH

Transplantation of Embryonic Stem Cells Improves Nerve Repair and Functional Recovery After Severe Sciatic Nerve Axotomy in Rats: Lin Cui, Jun Jiang, Ling Wei, Xin Zhou, Jamie L. Fraser, B. Joy Snider, Shan Ping Yu
Stem Cells May 1 2008: 1356 - 1365 . [Abstract] [Full Text] [PDF] [Supplemental Data]

In Vitro Model of Bromodeoxyuridine or Iron Oxide Nanoparticle Uptake by Activated Macrophages from Labeled Stem Cells: Implications for Cellular Therapy: Edyta Pawelczyk, Ali S. Arbab, Aneeka Chaudhry, Arun Balakumaran, Pamela G. Robey, Joseph A. Frank
Stem Cells May 1 2008: 1366 - 1375 . [Abstract] [Full Text] [PDF] [Supplemental Data]

Statin and Stromal Cell-Derived Factor-1 Additively Promote Angiogenesis by Enhancement of Progenitor Cells Incorporation into New Vessels: Hongwei Shao, Yaohong Tan, Darwin Eton, Zhe Yang, M. Georgina Uberti, Sen Li, Andrew Schulick, Hong Yu
Stem Cells May 1 2008: 1376 - 1384 . [Abstract] [Full Text] [PDF] [Supplemental Data]

LETTER TO THE EDITOR

Bone Marrow-Derived Stem Cells Do Not Reconstitute Spermatogenesis In Vivo: Bruno Lassalle, Marc Andrée Mouthon, Lydia Riou, Vilma Barroca, Mathieu Coureuil, François Boussin, Jacques Testart, Isabelle Allemand, Pierre Fouchet
Stem Cells May 1 2008: 1385 - 1386 . [Full Text] [PDF] [Supplemental Data]

Cover Illustration:

Cover Artist's depiction of an in vitro grown cell clone.